Evaluation of Anti-Seizure Medication Adjustment Leading to Seizure Freedom in Pre-Surgical Patients with Medically Refractory Epilepsy
Abstract number :
3.213
Submission category :
4. Clinical Epilepsy / 4C. Clinical Treatments
Year :
2023
Submission ID :
1146
Source :
www.aesnet.org
Presentation date :
12/4/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: Moustafa Mesha, MBBCh – University at Buffalo
Amanda Schwandt, DO – Epilepsy Fellow, Department of Neurology, University at Buffalo; Arie Weinstock, MD – Clinical professor, Department of Neurology, University at buffalo
Rationale:
Medically refractory epilepsy (MRE) is defined as failure to achieve seizure freedom despite a trial of two appropriately dosed anti-seizure medications (ASM). In such patients, the likelihood of failing a third ASM is up to 95% rendering them candidates for pre-surgical evaluation. Often in such circumstances, no further medication adjustments are made until invasive EEG monitoring or epilepsy surgery has been completed. In this study, we report a cohort of patients who underwent pre-surgical workup, were deemed appropriate surgical candidates, and subsequently achieved seizure freedom prior to surgical intervention with medication adjustment alone.
Clinical Epilepsy