Guidelines

The American Epilepsy Society is a trusted source of evidence-based clinical guidance for epilepsy specialists and other healthcare providers. 

AES Clinical Guidance in Development

• AES Management of Infantile Epilepsies Systematic Review Update and Guideline
• AES/ACNS Intraoperative Electrocorticography (ECoG) Systematic Review and Guideline
• AES/CNS Epilepsy Surgery Systematic Review and Guideline
• AES/NCS Status Epilepticus Systematic Review and Guideline

Evidence-Based Guidelines

• Teratogenesis, Perinatal, and Neurodevelopmental Outcomes After In Utero Exposure to Antiseizure Medication: Practice Guideline from AAN, AES, and SMFM (May 2024)
• Practice Guideline Update Summary: Efficacy and Tolerability of the New Antiepileptic Drugs I: Treatment of New-onset Epilepsy
• Practice Guideline Update Summary: Efficacy and Tolerability of the New Antiepileptic Drugs II: Treatment-resistant Epilepsy
• Practice Guideline Summary: SUDEP Incidence Rates and Risk Factors: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society
• Practice guideline summary: Use of fMRI in the presurgical evaluation of patients with epilepsy

• Evidence-Based Guideline: Treatment of Convulsive Status Epilepticus in Children and Adults: Report of the Guideline Committee of the American Epilepsy Society
  • Guideline for Treatment of Prolonged Seizures in Children and Adults 
  • A Treatment Algorithm that Comprises Three Phases of Treatment 
• Evidence-based Guideline: Management of First Unprovoked Seizure in Adults
• Evidence-based Guideline: Evaluation and Management of Concussion in Sports
• Evidence-based Guideline: Vagus Nerve Stimulation for the Treatment of Epilepsy
• Evidence-based Guideline: Antiepileptic Drug Selection for People with HIV/AIDS

2020 AES CPG Development Manual

AES Clinical Practice Guideline Development Manual (2020)
This manual outlines principles and processes intended to guide AES-led workgroups in the development of high-quality clinical guidance products consistent with broadly accepted, evidence-based principles and processes appropriate to the needs of the epilepsy clinical community.