Experience of Surgery for Drug Resistant Epilepsy in a Private Third-level Hospital
Abstract number :
1.412
Submission category :
9. Surgery / 9C. All Ages
Year :
2022
Submission ID :
2232881
Source :
www.aesnet.org
Presentation date :
12/3/2022 12:00:00 PM
Published date :
Nov 22, 2022, 05:28 AM
Authors :
Sofía Lucila Rodríguez Rivera, MD – Hospital Zambrano Hellion, TecSalud; José Antonio Infante Cantú, Pediatric Neurology – Pediatric Neurology – Hospital Zambrano Hellion, Tec Salud Monterrey Mexico; Héctor Ramón Martínez Rodríguez, Neurology – Neurology – Hospital Zambrano Hellion, Tec Salud Monterrey Mexico; Enrique Caro Osorio, Neurosurgery – Neurosurgery – Hospital Zambrano Hellion, Tec Salud Monterrey Mexico
Rationale: The worldwide prevalence of epilepsy is 7/1000 inhabitants. In 30%, there is drug resistance.1. For these patients, epilepsy surgery is a valid treatment alternative.2 Purpose: To present our experience of surgery for drug resistant epilepsy in a private third-level hospital.
Methods: Descriptive, retrospective, observational, cross-sectional study. Inclusion criteria: patients with drug resistant epilepsy and epilepsy surgery from January 2017 to June 2022. Data were obtained from clinical records and captured in Excel. Tests (measures of central tendency, chi square, student’s t) were applied in SPSS program.
Results: A total of 19 patients were included. Age: 3-75 years old, mean: 28.1±0.7. Male: 53%. Average age at the time of surgery: 14 years old. Mean age of onset of epilepsy: 5.5 years old. Time between onset-surgery: 7 years. Epileptogenic zone: frontal 26%, temporal 37%, hemispheric 5%, posterior 32%. Etiology: focal cortical dysplasia 16%, mesial temporal sclerosis 21%, low-grade tumor 32%, vascular malformation 21%, Rasmussen´s encephalitis 5%, Lennox-Gastaut syndrome 5%. Types of epilepsy surgery: temporal resection 21%, extra-temporal resection 16%, lesionectomy 53%, hemispherectomy 5%, callosotomy 5%. Seizure reduction (Engel): I 69%, II 21%, III 5%, IV 5%. Association was found between favorable response and early epilepsy surgery with statistical significance (p < 0.05).
Surgery