Ictal Central Apnea: An Overlooked Symptom in Temporal Lobe Seizures
Abstract number :
2.008
Submission category :
3. Neurophysiology / 3A. Video EEG Epilepsy-Monitoring
Year :
2021
Submission ID :
1825798
Source :
www.aesnet.org
Presentation date :
12/5/2021 12:00:00 PM
Published date :
Nov 22, 2021, 06:50 AM
Authors :
Stefano Meletti, MD, PhD - University of Modena and Reggio Emilia; Elisa Micalizzi, MD - University of Pavia; Anna Vaudano, MD, PhD - Neurology dept AOU Modena; Giada Giovannini, MD - Neurolgy dept AOU Modena; Giulia Turchi, MD - Neurology Dept AOU Modena
Rationale: Ictal respiratory changes have been mainly described as following generalized tonic-clonic seizures and recently considered as a biomarker for the risk of SUDEP (Sudden Unexpected Death in Epilepsy). Nonetheless modification of respiratory pattern can be related also to focal seizures, especially arising from the temporal lobe. Heart rate changes are often associated. Neurophysiological studies support the existence of a cortical network involving the limbic system that downstream modulates the brainstem respiratory center.
Methods: We report a case series of 5 patients (3 males, 2 females, aged 20-50 years) with Temporal Lobe Epilepsy admitted to our Epilepsy Monitoring Unit from January to May 2021 who underwent a Long Term Monitoring with a 10-20 EEG system integrated with ECG, SpO2, pulse-oximetry and thoraco-abdominal pneumography. We considered as an apnea a respiratory arrest of 5 or more seconds on the pneumographic channel, a desaturation a SpO2 value below 95% (mild 90-94%, moderate 75-89%, severe < 75%).
Neurophysiology