Localizing and Lateralizing Value of Peri-ictal Water Drinking in Focal Epilepsy
Abstract number :
2.114
Submission category :
4. Clinical Epilepsy / 4B. Clinical Diagnosis
Year :
2022
Submission ID :
2204223
Source :
www.aesnet.org
Presentation date :
12/4/2022 12:00:00 PM
Published date :
Nov 22, 2022, 05:24 AM
Authors :
Takashi Matsudaira, MD, PhD – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Yuhei Tanno, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Naotaka Usui, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Kentaro Tokumoto, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Hiroshi Ogawa, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Norihiko Kawaguchi, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Akihiko Kondo, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Takuji Nishida, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders; Yukitoshi Takahashi, none – National Epilepsy Center, NHO Shizuoka Institute of Epilepsy and Neurological Disorders
Rationale: The aim of our study was to investigate the localizing and lateralizing value of peri-ictal water drinking (PIWD) in patients with focal epilepsy.
Methods: We retrospectively reviewed 370 patients aged over 10 years-old who had underwent resective surgery. The patients with favorable postoperative seizure outcome (Engle class I) were included. PIWD was defined as the water drinking behavior during a seizure or up to 2 minutes post-ictally. We analyzed the PIWD occurrence on long-term video-EEG monitoring. The localizing value of PIWD was assessed, and then lateralizing value of PIWD was analyzed among the patients whose language dominants hemisphere was identified by WADA test or functional MRI.
Results: Among 240 patients included in our study, 23 patients (9.5%) exhibited PIWD. PIWD occurred more frequently in FLE (8 of 41 patients, 19.5%) than that in TLE (15 of 188 patients, 8.0%) (p = 0.04). In FLE, all but one underwent the resective surgery including medial frontal lobe. The localizing value of PIWD in TLE showed no statistical significance (p = 0.12), while that in FLE showed a statistical significance (p = 0.035: 8 of 41 patients with FLE and 15 of 199 with extra-FLE). The lateralizing value of PIWD in FLE and TLE showed no statistical significance (p = 0.69 and p = 0.26).This retrospective study was approved by the Ethics Committee of our institute.
Conclusions: Our study indicate that PIWD may represent a localizing sign of FLE. Whereas, contradictory to some previous reports, we could not find any evidence for the lateralizing value of PIWD in TLE.
Funding: None
Clinical Epilepsy