Abstracts

Periodic Lateralized Epileptiform Discharges (PLEDs): Causes and Clinical Courses

Abstract number : 1.069
Submission category : Clinical Neurophysiology-Clinical EEG
Year : 2006
Submission ID : 6203
Source : www.aesnet.org
Presentation date : 12/1/2006 12:00:00 AM
Published date : Nov 30, 2006, 06:00 AM

Authors :
1Sung-Hun Kim, 2Sanggun Lee, 3Jongbai Oh, and 1Hyunwoo Nam

We wanted to reveal the causes and the clinical courses in patients with periodic lateralized epileptic discharges (PLEDs) including the presence of ictal semiology., We reviewed clinical, imaging and EEG data of 52 patients with PLEDs in our hospital from January, 2002 to May, 2006. Recurrent episodes in one patient were counted as one because there was no difference among the attacks. In those cases, the etiology was usually remote and fixed., Ictal semiology was notable in 65%. Etiology was variable including encephalitis (27%), tumor (19%), acute vascular event (19%), metabolic encephalopathy (15%), remote vascular event (12%), hippocampal sclerosis (4%), and MELAS (2%). Acute etiology was extremely more frequent than remote one (84% vs. 16%). The mortality rate was 27%, which is similar to that of status epilepticus reported in recent studies., PLEDs are usually ictal responses mainly to acute brain insults. Mismatch between the character of the lesion and the clinical presentation should prompt the checking of EEG with corresponding treatment with AED.,
Neurophysiology