Polysomnographic Findings in Children With Juvenile Myoclonic Epilepsy
Abstract number :
3.267
Submission category :
6. Comorbidity (Somatic and Psychiatric)
Year :
2018
Submission ID :
505510
Source :
www.aesnet.org
Presentation date :
12/3/2018 1:55:12 PM
Published date :
Nov 5, 2018, 18:00 PM
Authors :
Pablo Jorrat, FLENI; Maria Elena Mazzola, FLENI; and Angeles Schteinschnaider, FLENI
Rationale: Objective: to analyze the sleep architecture using polysomnography (PSG) in patients with Juvenile Myoclonic Epilepsy JME (newly diagnosed and those on valproate drug). Methods: This study involved 19 patients with JME, 9 newly diagnosed patients and 10 on valproate (age: 16.5 ± 2.5 years; M:F=7:11) and 10 matched healthy controls (age 15 ± 2 years; M:F= 4:6). All patients underwent clinical assessment, electroencephalogram (EEG), and evaluation with sleep questionnaire and PSG. Results: PSG analysis revealed significant alterations in sleep architecture in the JME group in the form of reduced sleep efficiency, increased mean of sleep latency, increased % Wake after sleep onset (WASO) and decreased % REM sleep. Sleep questionnaire revealed poor quality of sleep in JME patients. Conclusions: Sleep quality and sleep architecture were significantly disturbed in JME, with improvement sleep efficiency in valproate treated patients. Funding: Personal funding