Pre-Implantation Entropy as a Marker of Vagus Nerve Stimulation (VNS) Efficacy in Drug-Resistant Epilepsy
Abstract number :
2.024
Submission category :
3. Neurophysiology / 3C. Other Clinical EEG
Year :
2023
Submission ID :
631
Source :
www.aesnet.org
Presentation date :
12/3/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: Irena Dolezalova, MD, PhD – St. Annes´University Hospital
Jan Chladek, co-author – The First-Deparmetn of Neurology – St. Anne´s University Hospital; Jan chrastina, co-author – The Department of Neurosurgery – St. Anne´s University Hospital; Tereza Jurkova, co-author – Institute of Biostatistics and Analyses – Masaryk University; Eva Zatloukalova, co-author – The First Deparmetn of Neurology – St. Anne´s University Hospital; Barbora Sklenarova, co-author – The First-Deparmetn of Neurology – St. Anne´s University Hospital; Milan Brazdil, co-author – The First-Deparmetn of Neurology – St. Anne´s University Hospital
Rationale:
Vagus nerve stimulation (VNS) is a therapeutic option in drug-resistant epilepsy. VNS leads to ≥ 50% seizure reduction in fifty to sixty percent of patients, called responders. The remaining forty to fifty percent of patients, called non-responders, exhibit seizure reduction < 50%. Our work mainly aims to differentiate between these two patient groups in pre-implantation EEG analysis by employing several entropy methods.
Neurophysiology