Significance of Chronic Epilepsy in Primary Brain Tumor
Abstract number :
2.292
Submission category :
Year :
2001
Submission ID :
201
Source :
www.aesnet.org
Presentation date :
12/1/2001 12:00:00 AM
Published date :
Dec 1, 2001, 06:00 AM
Authors :
O-J. Kim, Dr, Neurology, Pochon CHA University, Sungnam, Gyunggi-do, Republic of Korea; B. Lee, Dr, Neurology, Yonsei University, Seoul, Republic of Korea
RATIONALE: A small but significant proportion of patients with brain tumors continued to have seizures postoperatively. These could no all be explained simply by failure to adequately resect the tumor mass.
METHODS: We selected 99 patients who were admitted with seizure attacks and operated with primary brain tumor between 1993 and 2000 at Pochon CHA and Yonsei University Hospital. We divided patients into chronic epilepsy group(CEG) (seizure attack [gte] 1 year) and acute epilepsy group(AEG) (seizure attack [lt] 1 year). We investigated the differences of clinical, pathological, and laboratory findings between two groups.
RESULTS: Of 99 patients, 43 were CEG and 56 were AEG. Among the various factors, seizure recurrence(no etiology) rate was significantly higher in CEG than AEG(p[lt]0.05). But, the laboratory abnormalities and tumor residue or recurrence on MRI findings were significantly higher in AEG than CEG(p[lt]0.05). Glioblastoma were more frequently found in AEG and astrocytoma in CEG, but the differences were not statistically significant.
CONCLUSIONS: There were the differences of epileptogenesis between two groups. We suggest that the brain tumor patients with chronic epilepsy have to be investigated with extensive work-up including invasive electrophyosiologic study.