Surgical Outcomes in Pediatric Temporal Lobe Epilepsy Compared to Extratemporal Epilepsy Following Stereo-electroencephalography (sEEG) Monitoring
Abstract number :
3.403
Submission category :
9. Surgery / 9B. Pediatrics
Year :
2025
Submission ID :
262
Source :
www.aesnet.org
Presentation date :
12/8/2025 12:00:00 AM
Published date :
Authors :
Presenting Author: Himadri Patel, MD – Children's Hospital of Pittsburgh, UPMC
Leen Alkalbani, MD – Children's Hospital of Pittsburgh, UPMC
Emily Harford, MA – Children's Hospital of Pittsburgh, UPMC
Melissa Sutcliffe, PhD – Children's Hospital of Pittsburgh, UPMC
Sarah Laughlin, PhD – Children's Hospital of Pittsburgh, UPMC
Geetha Vasudevan, MD – Children's Hospital of Pittsburgh, UPMC
Nicholas Benjamin, MD – Children's Hospital of Pittsburgh, UPMC
Mikaela Speakes, MD – Children's Hospital of Pittsburgh, UPMC
Taylor Abel, MD – Children's Hospital of Pittsburgh, UPMC
William Welch, MD – Children's Hospital of Pittsburgh, UPMC
Ruba Al-Ramadhani, MD – Children's Hospital of Pittsburgh, UPMC
Rationale: This study aimed to evaluate and compare seizure outcomes in pediatric patients with drug-resistant epilepsy (DRE) following invasive monitoring using stereo-electroencephalography (sEEG), with a specific focus on differences between temporal lobe and extratemporal epilepsy to inform surgical decision making.
Methods: A retrospective chart review was conducted for data collection of pediatric patients with DRE who underwent sEEG at UPMC Children’s Hospital from 2019 to 2024. Patients included were characterized according to temporal lobe vs extratemporal lobe epilepsy. Relevant information regarding demographics, baseline seizure frequency, number of anti-seizure medications (ASMs) at follow-up, and type of post-sEEG intervention was collected and analyzed. Statistical analysis employed Chi-square tests for categorical variables and Mann-Whitney U tests for continuous variables, with significance set at p< 0.05.
Surgery