The Characteristics of Epilepsy in Children with Cerebral Palsy
Abstract number :
3.248
Submission category :
6. Cormorbidity (Somatic and Psychiatric)
Year :
2023
Submission ID :
684
Source :
www.aesnet.org
Presentation date :
12/4/2023 12:00:00 AM
Published date :
Authors :
Presenting Author: Jee Min Kim, MD – The Catholic University of Korea, Daejeon St. Mary's Hospital
Ji Yoon Han, MD, PhD – Pediatrics – The Catholic University of Korea, Daejeon St. Mary's Hospital
Rationale: Cerebral palsy (CP) is an umbrella term for nonprogressive motor diseases caused by insults to a developing brain. Patients with cerebral palsy have more epilepsy than general population. Our research aims in finding the characteristics of epilepsy and identify risk factors for epilepsy in children with cerebral palsy.
Methods: The medical record of pediatric patients (≤ 18 years of age) who visited pediatric neurology and/or rehabilitation department of a university affiliated tertiary hospital from January 2016 to December 2022, with magnetic resonance imaging (MRI), electroencephalogram (EEG) with minimum of two year follow up and diagnosed with cerebral palsy were reviewed retrospectively.
Results: Two hundred sixty-eight patients were included in the study. Prematurity is significantly higher in patients without epilepsy (65.7%) compared to patients with epilepsy (50.5%, p=0.02). Patients with asphyxia (29.3% vs. 13.0%) and brain injury which includes brain hemorrhage, infarction and meningoencephalitis (25.3% vs. 13.0%) are twice common in patients with epilepsy (p=0.001 and 0.013, respectively). Epilepsy group had significantly higher degree of gross motor impairment (51.5% in level 5 GMFCS-E&R vs. 11.2%, p< 0.001) and intellectual disability (85.9% vs. 41.4%, p < 0.001). A total of 10.8% of CP patients had drug resistant epilepsy (DRE) and most risk factors were comparable between DRE and controlled epilepsy with an exception of occipitofrontal circumference.
Cormorbidity (Somatic and Psychiatric)