Authors :
Areej Javeid, MBBS – Allama Iqbal Medical College
Presenting Author: Javeria Javeid, MBBS – University of Florida
Wajeeh Hassan, MBBS – Allama Iqbal Medical College
Zain Ali Nadeem, MBBS – Allama Iqbal Medical College
Rayyan Nabi, MBBS – drrayyannabi03@gmail.com
Tabeer Zahid, MBBS – Foundation University Medical College (FUSH)
khadija Khalid, MBBS – Allama Iqbal Medical College
Kashmala Zafar, MBBS – Al nafees medical college
Syed Hashim Ali Inam, MD – Marshall University Joan C. Edwards School of Medicine, Department of Neurology
Gabrielle Hammers, MS3 – Marshall University School of Medicine
Samirna Hanif, MD – Marshall University
Rationale:
Epilepsy is one of the most common neurological disorders, affecting around 51.7 million people worldwide in 2021: 658 cases per 100000 people. Epileptic seizures can affect respiration, and lead to aspiration pneumonia and other respiratory diseases, which can prove fatal. In this study, we aim to determine the trends and disparities in respiratory disease-related mortality among patients with epilepsy in the United States (US) from 1999 to 2020.Methods:
We obtained data from the Centers for Disease Control and Prevention Wide-ranging Online Data for Epidemiologic Research (CDC WONDER) database for adults ( >25 years) in the U.S. from 1999 to 2020, with respiratory disease and epilepsy listed anywhere on the death certificates, either as the underlying or a contributing cause of death. Crude mortality rates (CMRs) and age-adjusted mortality rates (AAMRs) were calculated per 100,000 people, along with 95% confidence intervals (CIs). We used the Joinpoint Regression Program to analyze temporal trends by calculating the annual percent change (APC) in the rates. A P-value < 0.05 was considered statistically significant.